“The well-known lethal triad of acidosis, hypothermia, and coagulopathy has become increasingly recognized as an interrelated and synergistic phenomenon that contributes to morbidity and mortality in trauma patients. Current strategies of resuscitation emphasize early and aggressive measures to address these factors. One of the largest contributing factors to the development of the lethal triad is uncontrolled bleeding. Although significant extremity bleeding may be stopped through the use of tourniquets, there are many situations and injury locations in which tourniquets are not effective or are anatomically impossible to place proximal to the injury.”

Causey: The efficacy of Combat Gauze in extreme physiologic conditions. Journal of Surgical Research XXX (2012) 1 – 5.